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以下產(chǎn)品用于研究當(dāng)關(guān)鍵結(jié)構(gòu)元件改變時(shí)對(duì)寡核苷酸活性的影響。7-脫氮嘌呤單體缺乏對(duì)氫鍵合至關(guān)重要的基團(tuán)。7-Deaza-8-aza-A和7-deaza-8-aza-G（PPG）單體是A和G的異構(gòu)體，并且具有相似的電子密度。它們?cè)诠押塑账嶂械拇嬖谙鄬?duì)于A和G略微穩(wěn)定。與G不同，PPG不會(huì)導(dǎo)致聚集，并且可以容易地制備和分離富含G的寡核苷酸。在5'-末端具有PPG的5'-熒光素寡核苷酸比等同的G寡核苷酸淬滅得少得多。作為胸苷的嘌呤類似物，7-脫氮-2'-脫氧黃嘌呤核苷（7-deaza-dX）有望對(duì)三鏈體的DNA結(jié)構(gòu)產(chǎn)生有趣的影響。7-Deaza-dX還與2,4-二氨基嘧啶核苷類似物形成非標(biāo)準(zhǔn)堿基對(duì)。標(biāo)準(zhǔn)核堿基具有未共享的電子對(duì)，其突出到雙鏈DNA的小溝中。與DNA，聚合酶，逆轉(zhuǎn)錄酶，限制酶等相互作用的酶可以使用氫鍵供體基團(tuán)與小溝中的氫鍵受體接觸。3-Deaza-2'-deoxyadenosine非常有趣，因?yàn)樗３至顺Ｒ?guī)Watson-Crick氫與T鍵合的能力，但缺乏通常由N3提供的3-位的電子對(duì)。
5'-二甲氧基三苯甲基-N-苯甲酰基-7-脫氮-2'-脫氧腺苷，3' - [（2-氰基乙基） - （N，N-二異丙基）] - 亞磷酰胺
分子式：C 4 8 H 5 3 N 6 O 7 P.
MW：856.96
FW：312.22
稀釋劑：無水乙腈
耦合：合成器制造商推薦的標(biāo)準(zhǔn)方法無需更改。
去保護(hù)：合成器制造商推薦的標(biāo)準(zhǔn)方法無需更改。
儲(chǔ)存：冷藏，高2-8°C，干燥
溶液中的穩(wěn)定性：類似于dA，C，G，T-CE亞磷酰胺
10-1001-95
50µm
10-1001-90
100µm
10-1001-02
0.25g
Item | Nucleoside | λMax-1 | Emax-1 | λMax-2 | Emax-2 | E260 |
|
| (nm) | (ml/µmole) | nm | (ml/µmole) | (ml/µmole) |
10-1001 | 7-deaza-dA | 270 | 11.3 |
|
| 9.4 |
下表顯示了包裝尺寸數(shù)據(jù)，以及基于正常灌注程序的溶液，稀釋液和近似偶聯(lián)。請(qǐng)與各種合成器鏈接以獲取更詳細(xì)的使用信息。
ABI 392/394 | |||||||||
Cat.No. | Pack | Grams/ | 0.1M Dil. | LV40 | LV200 | 40nm | 0.2µm | 1µm | 10µm |
Approximate Number of Additions | |||||||||
10-1001-02 | 0.25grams | .25grams | 2.92 | 84 | 50.4 | 31.5 | 22.91 | 16.8 | 4.2 |
10-1001-90 | 100µmoles | .086grams | 1 | 20 | 12 | 7.5 | 5.45 | 4 | 1 |
10-1001-95 | 50µmoles | .043grams | .5 | 3.33 | 2 | 1.25 | .91 | .67 | .17 |
Expedite | |||||||||
Cat.No. | Pack | Grams/ | Dilution | Molarity | 50nm | 0.2µm | 1µm | 15µm |
|
Approximate Number of Additions | |||||||||
10-1001-02 | 0.25grams | .25grams | 4.35 | .07 | 80.6 | 50.38 | 36.64 | 5.04 |
|
10-1001-90 | 100µmoles | .086grams | 1.5 | .07 | 23.6 | 14.75 | 10.73 | 1.48 |
|
10-1001-95 | 50µmoles | .043grams | .75 | .07 | 8.6 | 5.38 | 3.91 | .54 |
|
貨號(hào) | 品名 | 規(guī)格 | 目錄價(jià) | 品牌 |
10-0001-02 | dA-5'-CE Phosphoramidite | 0.25grams | 1275 | glen research |
10-0001-05 | dA-5'-CE Phosphoramidite | 0.5grams | 2550 | glen research |
10-0001-10 | dA-5'-CE Phosphoramidite | 1.0gram | 5100 | glen research |
10-0101-02 | dC-5'-CE Phosphoramidite | 0.25grams | 1275 | glen research |
10-0101-05 | dC-5'-CE Phosphoramidite | 0.5grams | 2550 | glen research |
10-0101-10 | dC-5'-CE Phosphoramidite | 1.0gram | 5100 | glen research |
10-0301-02 | dT-5'-CE Phosphoramidite | 0.25grams | 1275 | glen research |
10-0301-05 | dT-5'-CE Phosphoramidite | 0.5grams | 2550 | glen research |
10-0301-10 | dT-5'-CE Phosphoramidite | 1.0gram | 5100 | glen research |
10-1000-02 | dA-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1000-02M | dA-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1000-05 | dA-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1000-05M | dA-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1000-10 | dA-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1000-10M | dA-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1000-1C | dA-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1000-1S | dA-CE Phosphoramidite | 10.0grams | 8500 | glen research |
10-1000-20 | dA-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1000-2C | dA-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1000-40 | dA-CE Phosphoramidite | 4.0grams | 3400 | glen research |
10-1000-50 | dA-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1000-5S | dA-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1000-C2 | dA-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1000-C5 | dA-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1001-02 | 7-Deaza-dA-CE Phosphoramidite | 0.25grams | 16575 | glen research |
10-1001-90 | 7-Deaza-dA-CE Phosphoramidite | 100µmoles | 6035 | glen research |
10-1001-95 | 7-Deaza-dA-CE Phosphoramidite | 50µmoles | 3017.5 | glen research |
10-1002-02 | dA+dG-CE Phosphoramidite | 0.25grams | 680 | glen research |
10-1003-02 | N6-Me-dA-CE Phosphoramidite | 0.25grams | 8415 | glen research |
10-1003-90 | N6-Me-dA-CE Phosphoramidite | 100µmoles | 2762.5 | glen research |
10-1004-02 | 3'-dA-CE Phosphoramidite | 0.25grams | 16575 | glen research |
10-1004-90 | 3'-dA-CE Phosphoramidite | 100µmoles | 6035 | glen research |
10-1004-95 | 3'-dA-CE Phosphoramidite | 50µmoles | 3017.5 | glen research |
10-1006-02 | Etheno-dA-CE Phosphoramidite | 0.25grams | 4335 | glen research |
10-1006-90 | Etheno-dA-CE Phosphoramidite | 100µmoles | 1785 | glen research |
10-1007-02 | 8-Br-dA-CE Phosphoramidite | 0.25grams | 5015 | glen research |
10-1007-90 | 8-Br-dA-CE Phosphoramidite | 100µmoles | 1955 | glen research |
10-1008-02 | 8-oxo-dA-CE Phosphoramidite | 0.25grams | 6035 | glen research |
10-1008-90 | 8-oxo-dA-CE Phosphoramidite | 100µmoles | 2295 | glen research |
10-1010-02 | dC-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1010-02M | dC-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1010-05 | dC-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1010-05M | dC-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1010-10 | dC-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1010-10M | dC-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1010-1C | dC-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1010-1S | dC-CE Phosphoramidite | 10.0grams | 8500 | glen research |
10-1010-20 | dC-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1010-2C | dC-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1010-40 | dC-CE Phosphoramidite | 4.0grams | 3400 | glen research |
10-1010-50 | dC-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1010-5S | dC-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1010-C2 | dC-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1010-C5 | dC-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1013-02 | dC+dT-CE Phosphoramidite | 0.25grams | 680 | glen research |
10-1014-02 | pdC-CE Phosphoramidite | 0.25grams | 4165 | glen research |
10-1014-05 | pdC-CE Phosphoramidite | 0.5grams | 8330 | glen research |
10-1014-90 | pdC-CE Phosphoramidite | 100µmoles | 1445 | glen research |
10-1015-02 | Ac-dC-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1015-02M | Ac-dC-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1015-05 | Ac-dC-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1015-05M | Ac-dC-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1015-10 | Ac-dC-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1015-10M | Ac-dC-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1015-1C | Ac-dC-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1015-1S | Ac-dC-CE Phosphoramidite | 10.0grams | 8500 | glen research |
10-1015-20 | Ac-dC-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1015-2C | Ac-dC-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1015-40 | Ac-dC-CE Phosphoramidite | 4.0grams | 3400 | glen research |
10-1015-50 | Ac-dC-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1015-5S | Ac-dC-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1015-C2 | Ac-dC-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1015-C5 | Ac-dC-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1016-02 | TMP-F-dU-CE Phosphoramidite | 0.25grams | 8415 | glen research |
10-1016-90 | TMP-F-dU-CE Phosphoramidite | 100µmoles | 3315 | glen research |
10-1017-02 | Pyrrolo-dC-CE Phosphoramidite | 0.25grams | 11475 | glen research |
10-1017-90 | Pyrrolo-dC-CE Phosphoramidite | 100µmoles | 3740 | glen research |
10-1017-95 | Pyrrolo-dC-CE Phosphoramidite | 50µmoles | 1870 | glen research |
10-1018-02 | 5-Me-dC Brancher Phosphoramidite | 0.25grams | 8585 | glen research |
10-1018-90 | 5-Me-dC Brancher Phosphoramidite | 100µmoles | 3485 | glen research |
10-1019-02 | Amino-Modifier C6 dC | 0.25grams | 7650 | glen research |
10-1019-90 | Amino-Modifier C6 dC | 100µmoles | 3825 | glen research |
10-1020-02 | dG-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1020-02M | dG-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1020-05 | dG-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1020-05M | dG-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1020-10 | dG-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1020-10M | dG-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1020-1C | dG-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1020-1S | dG-CE Phosphoramidite | 10.0grams | 8500 | glen research |
10-1020-20 | dG-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1020-2C | dG-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1020-40 | dG-CE Phosphoramidite | 4.0grams | 3400 | glen research |
10-1020-50 | dG-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1020-5S | dG-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1020-C2 | dG-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1020-C5 | dG-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1021-02 | 7-deaza-dG-CE Phosphoramidite | 0.25grams | 16575 | glen research |
10-1021-90 | 7-deaza-dG-CE Phosphoramidite | 100µmoles | 6035 | glen research |
10-1021-95 | 7-deaza-dG-CE Phosphoramidite | 50µmoles | 3017.5 | glen research |
10-1023 | dA+dC+dG+dT-CE Phosphoramidite Mix | 1.0gram | 680 | glen research |
10-1027-02 | 8-Br-dG-CE Phosphoramidite | 0.25grams | 4335 | glen research |
10-1027-90 | 8-Br-dG-CE Phosphoramidite | 100µmoles | 1785 | glen research |
10-1028-02 | 8-oxo-dG-CE Phosphoramidite | 0.25grams | 16575 | glen research |
10-1028-90 | 8-oxo-dG-CE Phosphoramidite | 100µmoles | 6035 | glen research |
10-1028-95 | 8-oxo-dG-CE Phosphoramidite | 50µmoles | 3017.5 | glen research |
10-1029-02 | dmf-dG-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1029-02M | dmf-dG-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1029-05 | dmf-dG-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1029-05M | dmf-dG-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1029-10 | dmf-dG-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1029-10M | dmf-dG-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1029-1C | dmf-dG-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1029-1S | dmf-dG-CE Phosphoramidite | 10.0grams | 8500 | glen research |
10-1029-20 | dmf-dG-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1029-2C | dmf-dG-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1029-40 | dmf-dG-CE Phosphoramidite | 4.0grams | 3400 | glen research |
10-1029-50 | dmf-dG-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1029-5S | dmf-dG-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1029-C2 | dmf-dG-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1029-C5 | dmf-dG-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1030-02 | dT-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1030-02M | dT-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1030-05 | dT-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1030-05M | dT-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1030-10 | dT-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1030-10M | dT-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1030-1C | dT-CE Phosphoramidite | 1.0gram | 850 | glen research |
10-1030-1S | dT-CE Phosphoramidite | 10.0grams | 8500 | glen research |
10-1030-20 | dT-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1030-2C | dT-CE Phosphoramidite | 2.0grams | 1700 | glen research |
10-1030-40 | dT-CE Phosphoramidite | 4.0grams | 3400 | glen research |
10-1030-50 | dT-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1030-5S | dT-CE Phosphoramidite | 5.0grams | 4250 | glen research |
10-1030-C2 | dT-CE Phosphoramidite | 0.25grams | 212.5 | glen research |
10-1030-C5 | dT-CE Phosphoramidite | 0.5grams | 425 | glen research |
10-1031-02 | 5'-OMe-dT-CE Phosphoramidite | 0.25grams | 6035 | glen research |
10-1031-90 | 5'-OMe-dT-CE Phosphoramidite | 100µmoles | 2295 | glen research |
10-1032-02 | O4-Me-dT-CE Phosphoramidite | 0.25grams | 6035 | glen research |
10-1032-90 | O4-Me-dT-CE Phosphoramidite | 100µmoles | 2295 | glen research |
10-1034-02 | 4-Thio-dT-CE Phosphoramidite | 0.25grams | 11475 | glen research |
10-1034-90 | 4-Thio-dT-CE Phosphoramidite | 100µmoles | 5015 | glen research |
10-1034-95 | 4-Thio-dT-CE Phosphoramidite | 50µmoles | 2805 | glen research |
10-1035-02 | Carboxy-dT | 0.25grams | 6120 | glen research |
10-1035-90 | Carboxy-dT | 100µmoles | 3060 | glen research |
10-1036-02 | 2-Thio-dT-CE Phosphoramidite | 0.25grams | 11475 | glen research |
10-1036-90 | 2-Thio-dT-CE Phosphoramidite | 100µmoles | 5015 | glen research |
10-1036-95 | 2-Thio-dT-CE Phosphoramidite | 50µmoles | 2805 | glen research |
10-1037-02 | Amino-Modifier C2 dT | 0.25grams | 6120 | glen research |
10-1037-05 | Amino-Modifier C2 dT | 0.5grams | 12240 | glen research |
10-1037-90 | Amino-Modifier C2 dT | 100µmoles | 3060 | glen research |
10-1038-02 | Biotin-dT | 0.25grams | 10625 | glen research |
10-1038-90 | Biotin-dT | 100µmoles | 5525 | glen research |
10-1038-95 | Biotin-dT | 50µmoles | 2847.5 | glen research |
10-1039-02 | Amino-Modifier C6 dT | 0.25grams | 6120 | glen research |
10-1039-05 | Amino-Modifier C6 dT | 0.5grams | 12240 | glen research |
10-1039-90 | Amino-Modifier C6 dT | 100µmoles | 3060 | glen research |
10-1040-02 | dI-CE Phosphoramidite | 0.25grams | 2040 | glen research |
10-1040-90 | dI-CE Phosphoramidite | 100µmoles | 850 | glen research |
10-1041-02 | 2'-DeoxyNebularine-CE Phosphoramidite (Purine) | 0.25grams | 4335 | glen research |
10-1041-90 | 2'-DeoxyNebularine-CE Phosphoramidite (Purine) | 100µmoles | 1785 | glen research |
10-1042-02 | O6-Phenyl-dI-CE Phosphoramidite | 0.25grams | 6035 | glen research |
10-1042-90 | O6-Phenyl-dI-CE Phosphoramidite | 100µmoles | 2295 | glen research |
10-1044-02 | 5-Nitroindole-CE Phosphoramidite | 0.25grams | 5525 | glen research |
10-1044-90 | 5-Nitroindole-CE Phosphoramidite | 100µmoles | 2125 | glen research |
10-1046-02 | 2-Aminopurine-CE Phosphoramidite | 0.25grams | 6035 | glen research |
10-1046-90 | 2-Aminopurine-CE Phosphoramidite | 100µmoles | 2295 | glen research |
10-1047-02 | dP-CE Phosphoramidite | 0.25grams | 10115 | glen research |
10-1047-90 | dP-CE Phosphoramidite | 100µmoles | 3315 | glen research |
10-1048-02 | dK-CE Phosphoramidite | 0.25grams | 10115 | glen research |
10-1048-90 | dK-CE Phosphoramidite | 100µmoles | 3315 | glen research |
10-1049-02 | dP+dK-CE Phosphoramidite | 0.25grams | 10115 | glen research |
10-1049-90 | dP+dK-CE Phosphoramidite | 100µmoles | 3315 | glen research |
10-1050-02 | dU-CE Phosphoramidite | 0.25grams | 1700 | glen research |
10-1050-90 | dU-CE Phosphoramidite | 100µmoles | 595 | glen research |
10-1051-02 | O4-Triazolyl-dU-CE Phosphoramidite | 0.25grams | 6035 | glen research |
10-1051-90 | O4-Triazolyl-dU-CE Phosphoramidite | 100µmoles | 2295 | glen research |
10-1052-02 | 4-Thio-dU-CE Phosphoramidite | 0.25grams | 11475 | glen research |
10-1052-90 | 4-Thio-dU-CE Phosphoramidite | 100µmoles | 5015 | glen research |
10-1052-95 | 4-Thio-dU-CE Phosphoramidite | 50µmoles | 2805 | glen research |
10-1053-02 | 5-OH-dU-CE Phosphoramidite | 0.25grams | 11475 | glen research |
10-1053-90 | 5-OH-dU-CE Phosphoramidite | 100µmoles | 3825 | glen research |
10-1054-02 | pdU-CE Phosphoramidite | 0.25grams | 3315 | glen research |
10-1054-05 | pdU-CE Phosphoramidite | 0.5grams | 6630 | glen research |
10-1054-90 | pdU-CE Phosphoramidite | 100µmoles | 1105 | glen research |
10-1055-02 | 2'-deoxypseudoU-CE Phosphoramidite | 0.25grams | 16575 | glen research |
10-1055-90 | 2'-deoxypseudoU-CE Phosphoramidite | 100µmoles | 6035 | glen research |
10-1055-95 | 2'-deoxypseudoU-CE Phosphoramidite | 50µmoles | 3017.5 | glen research |
10-1056-02 | Fluorescein-dT Phosphoramidite | 0.25grams | 11475 | glen research |
上海起發(fā)實(shí)驗(yàn)試劑有限公司是實(shí)驗(yàn)試劑一站式采購服務(wù)商
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3：提供加急服務(wù)，貨品一般1-2周到貨。
4：富有競爭力的價(jià)格優(yōu)勢，絕大部分價(jià)格有優(yōu)勢。
5：多年積累良好的信譽(yù)，大部分客戶提供貨到付款服務(wù)。客戶包括清華、北大、交大、復(fù)旦、中山等100多所高校，ROCHE，阿斯利康、國藥、fisher等知藥企。
6：我們還是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech；sysy,TriLink BioTechnologies,Inc；worthington-biochem,zyagen等幾十家國外公司授權(quán)代理。
7：我們還是invitrogen,qiagen,MiraiBioam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等知*批發(fā)，歡迎合作。
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